2,4-Difluoroaniline

CAS367-25-9

Ngā āhuatanga matū: he matū hinuhinu he kōwhai mā.

Ngā Whakamahinga: Ko te 2,4-Difluoroaniline he takawaenga i roto i te hanga rauropi. I roto i ngā rongoā, ka whakamahia hei hanga i te waikawa difluorophenylsalicylic me te waikawa polyfluorodiphenyl. Ko te waikawa difluorophenylsalicylic he rongoā anti-inflammatory kore-steroidal (NSAID) waikawa carboxylic, ko te ingoa kore-motuhake o te ao (INN) ko Diflunisal. Ahakoa kāore i te rōpū acetyl o te aspirin tēnei matū hou, kei roto he rōpū difluorophenyl, ka iti ake ngā pānga taha antiplatelet, he ngawari ake ngā tauhohenga puku, ā, he 8-12 hāora te roa o te mahi. Koinei pea te rongoā waikawa salicylic tino whai hua. He takawaenga nui hoki i roto i te hanga patupatu.

Te tātai ngota C6H5F2N,

taumaha ngota 129.11,

Nama EINECS 206-687-5

Te ira rewa -7.5 °C (iritihia)

Te pūmahana koropupū 170 °C/753 mmHg (lit.)

Kiato 1.268 g/mL i te 25 °C (i te rama)

Taupū whakaata n20/D 1.506 (lit.)

Pūwāhi mura 145 °F

Tikanga Whakaputa 1. Tikanga Whakaiti 2,4-Difluoronitrobenzene: Ka tāpirihia te paura rino me te otinga wai ammonium chloride ki tētahi tauhohenga whakaiti, ka whakamahanahia kia reflux, kātahi ka tāpirihia te 2,4-difluoronitrobenzene mā te maturuturu. Kia oti te tāpiri, refluxhia mō ngā haora e 2. Kia oti te tauhohenga, ka whakamaroketia te hua ki te mamaoa, ka wehea e Chemicalbook, ka whakamaroketia ki te konupūmā chloride kia whiwhi ai i tētahi hua whai mana me te hua o te 87%. 2. I whiwhihia mai i te 1,2,4-trichlorobenzene mā te nitration, te fluorination, me te dechlorination whakaiti; i whiwhihia rānei mai i te m-phenylenediamine mā te diazotization, te whakakapinga, te nitration, me te whakaiti.

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